Iihara M [Therapeutic strategy for pheochromocytoma.] [English Abstract, Journal Article] Gan To Kagaku Ryoho 2009 Oct; 36(10):1623-6.
Pheochromocytoma is the most common type of neuroendocrine tumor arising from the adrenal gland. Pheochromocytoma has been termed a 10% tumor because roughly 10% of such tumors are malignant, multifocal, bilateral, and arise in extra-adrenal sites. During the last decade, laparoscopic adrenalectomy has been the standard method to remove pheochromocytomas. Adrenal-sparing laparoscopic surgery is a treatment of choice for bilateral pheochromocytomas. Cyclophosphamide, vincristine and dacarbazine combined chemotherapy and 131I-MIBG therapy are required for the treatment of metastatic or unresectable malignant pheochromocytoma.
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